Australian clinical-stage photodynamic therapy

Designed to treat prostate cancer and preserve function.

ImmunoPDT is a clinical-stage, function-preserving photodynamic therapy for early prostate cancer, designed to treat the cancer while aiming to preserve continence and sexual function.

A senior research scientist at a laboratory bench
83.3%
cancer-specific survival in the audited Phase 1 cohort (30 of 36)
USANZ ASM Perth 2025 poster, Murphy, Sali, Garama
The two current options
Active surveillance
Radical treatment

Active surveillance treats nothing. Radical treatment risks lasting harm. ImmunoPDT is designed to close that gap, treating the cancer while aiming to preserve function.

How it works

Oral Immuno1, activated by targeted red light.

medication

Oral administration

The patient receives Immuno1, an oral photosensitising agent.

my_location

Localises in target tissue

Immuno1 is formulated to be taken up preferentially by prostate tissue, a key design improvement over earlier photodynamic therapies.

light_mode

Targeted light activation

Once the agent is taken up, a red-light diffuser placed in the prostate activates it (660 nm), which is designed to destroy the tumour locally and to prompt a local immune response, the "Immuno" in ImmunoPDT.

Evidence

Ten years of human follow-up. An active Phase 2.

View the evidence
An older couple's clasped hands resting on a table
83.3%
cancer-specific survival in the audited Phase 1 cohort (30 of 36).
USANZ ASM Perth 2025 poster, Murphy, Sali, Garama
15 of 21
PSA stable-or-better in Phase 2 (of 21 patients followed > 6 months; 28 accruing at July 2023).
Murphy ANZUP ASM 2023 poster
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A photodynamic therapy with potential across a range of solid tumours, starting with prostate, the most clinically and commercially significant.

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